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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50450395'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50450395
PNG
(CHEMBL318600)
Show SMILES CCCCCCCC[C@H](SCCCCCC)C(=O)Nc1c(SC)cc[n+](C)c1SC
Show InChI InChI=1S/C24H42N2OS3/c1-6-8-10-12-13-14-16-21(30-19-15-11-9-7-2)23(27)25-22-20(28-4)17-18-26(3)24(22)29-5/h17-18,21H,6-16,19H2,1-5H3/p+1/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
n/an/a 160n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...

Bioorg Med Chem Lett 5: 295-300 (1995)


BindingDB Entry DOI: 10.7270/Q29Z94WS
More data for this
Ligand-Target Pair