Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol regulatory element-binding protein 2' and Ligand = 'BDBM50351539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol regulatory element-binding protein 2 (Homo sapiens (Human))	BDBM50351539 (CHEMBL1824674) Show SMILES CCCc1cc(ccn1)-c1nc(cs1)-c1ccc(NS(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C21H19N3O2S3/c1-2-4-18-13-16(10-11-22-18)21-23-19(14-28-21)15-6-8-17(9-7-15)24-29(25,26)20-5-3-12-27-20/h3,5-14,24H,2,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...				J Med Chem 54: 4923-7 (2011) Article DOI: 10.1021/jm200304y BindingDB Entry DOI: 10.7270/Q2NG4R0Z
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