Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein' and Ligand = 'BDBM490783'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stimulator of interferon genes protein (Human)	BDBM490783 (US10968242, Example 13 Peak 2) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1C[C@@H]2OP(S)(=O)O[C@@H]3[C@@H](CSP(S)(=O)O[C@@H]1[C@H]2O)O[C@H]([C@@H]3F)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23FN10O7P2S3/c21-10-15-9(35-20(10)31-6-29-12-17(23)25-4-27-19(12)31)2-43-40(34,42)38-14-7(1-8(13(14)32)36-39(33,41)37-15)30-5-28-11-16(22)24-3-26-18(11)30/h3-10,13-15,20,32H,1-2H2,(H,33,41)(H,34,42)(H2,22,24,26)(H2,23,25,27)/t7-,8+,9-,10-,13+,14+,15-,20-,39?,40?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...				US Patent US10968242 (2021) BindingDB Entry DOI: 10.7270/Q27W6GB9
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM490783 (US10968242, Example 13 Peak 2) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1C[C@@H]2OP(S)(=O)O[C@@H]3[C@@H](CSP(S)(=O)O[C@@H]1[C@H]2O)O[C@H]([C@@H]3F)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23FN10O7P2S3/c21-10-15-9(35-20(10)31-6-29-12-17(23)25-4-27-19(12)31)2-43-40(34,42)38-14-7(1-8(13(14)32)36-39(33,41)37-15)30-5-28-11-16(22)24-3-26-18(11)30/h3-10,13-15,20,32H,1-2H2,(H,33,41)(H,34,42)(H2,22,24,26)(H2,23,25,27)/t7-,8+,9-,10-,13+,14+,15-,20-,39?,40?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.98E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...				US Patent US10968242 (2021) BindingDB Entry DOI: 10.7270/Q27W6GB9
					More data for this Ligand-Target Pair