Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein' and Ligand = 'BDBM490797'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stimulator of interferon genes protein (Human)	BDBM490797 (US10968242, Example 20 Peak 2) Show SMILES Cn1cnc2n(cnc2c1=O)[C@@H]1C[C@@H]2OP(O)(=O)O[C@@H]3[C@@H](COP(S)(=O)O[C@@H]1[C@H]2O)O[C@H]([C@@H]3F)n1cnc2c1ncn(C)c2=O |r| Show InChI InChI=1S/C22H25FN8O11P2S/c1-28-5-26-18-13(20(28)33)24-7-30(18)9-3-10-15(32)16(9)42-44(37,45)38-4-11-17(41-43(35,36)40-10)12(23)22(39-11)31-8-25-14-19(31)27-6-29(2)21(14)34/h5-12,15-17,22,32H,3-4H2,1-2H3,(H,35,36)(H,37,45)/t9-,10+,11-,12-,15+,16+,17-,22-,44?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...				US Patent US10968242 (2021) BindingDB Entry DOI: 10.7270/Q27W6GB9
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM490797 (US10968242, Example 20 Peak 2) Show SMILES Cn1cnc2n(cnc2c1=O)[C@@H]1C[C@@H]2OP(O)(=O)O[C@@H]3[C@@H](COP(S)(=O)O[C@@H]1[C@H]2O)O[C@H]([C@@H]3F)n1cnc2c1ncn(C)c2=O |r| Show InChI InChI=1S/C22H25FN8O11P2S/c1-28-5-26-18-13(20(28)33)24-7-30(18)9-3-10-15(32)16(9)42-44(37,45)38-4-11-17(41-43(35,36)40-10)12(23)22(39-11)31-8-25-14-19(31)27-6-29(2)21(14)34/h5-12,15-17,22,32H,3-4H2,1-2H3,(H,35,36)(H,37,45)/t9-,10+,11-,12-,15+,16+,17-,22-,44?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...				US Patent US10968242 (2021) BindingDB Entry DOI: 10.7270/Q27W6GB9
					More data for this Ligand-Target Pair