Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-K receptor (Homo sapiens (Human)) | BDBM50366377 (CHEMBL334721 | MEN-10627) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Menarini Ricerche S.p.A. Curated by ChEMBL | Assay Description Binding affinity towards Tachykinin receptor 2 | J Med Chem 43: 4041-4 (2000) Article DOI: 10.1021/jm0010217 BindingDB Entry DOI: 10.7270/Q2Z322CV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (HAMSTER) | BDBM50366377 (CHEMBL334721 | MEN-10627) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding affinity of compound against [125I]NKA binding to neurokinin-2 (NK-2) receptor in hamster urinary bladder | Bioorg Med Chem Lett 7: 31-36 (1997) Article DOI: 10.1016/S0960-894X(96)00570-7 BindingDB Entry DOI: 10.7270/Q2KD1ZDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (HAMSTER) | BDBM50366377 (CHEMBL334721 | MEN-10627) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards Tachykinin receptor 2 using [125I]iodohistidyl-NKA (0.1 nM)) as radioligand | Bioorg Med Chem Lett 5: 1445-1450 (1995) Article DOI: 10.1016/0960-894X(95)00254-Q BindingDB Entry DOI: 10.7270/Q2GX4C27 | |||||||||||
More data for this Ligand-Target Pair |