Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Homo sapiens (Human)) | BDBM50030130 ((S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cells | J Med Chem 36: 2044-5 (1993) BindingDB Entry DOI: 10.7270/Q2959GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50030130 ((S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance P | J Med Chem 37: 1269-74 (1994) BindingDB Entry DOI: 10.7270/Q2S75FCC | |||||||||||
More data for this Ligand-Target Pair |