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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50030181'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(GUINEA PIG)		BDBM50030181
PNG
((R)-4-Hydroxy-1-(1-methyl-1H-indole-3-carbonyl)-py...)
Show SMILES CN(Cc1ccccc1)C(=O)[C@@H](Cc1cccc(c1)C(F)(F)F)NC(=O)C1C[C@@H](O)CN1C(=O)c1cn(C)c2ccccc12
Show InChI InChI=1S/C33H33F3N4O4/c1-38-20-26(25-13-6-7-14-28(25)38)31(43)40-19-24(41)17-29(40)30(42)37-27(16-22-11-8-12-23(15-22)33(34,35)36)32(44)39(2)18-21-9-4-3-5-10-21/h3-15,20,24,27,29,41H,16-19H2,1-2H3,(H,37,42)/t24-,27-,29?/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro binding affinity against substance P receptor using [3H]SP as radioligand in guinea pig lung membrane

J Med Chem 37: 2090-9 (1994)


BindingDB Entry DOI: 10.7270/Q23779BT
More data for this
Ligand-Target Pair