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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50049329'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50049329
PNG
(CHEMBL350846 | N-{3-(1H-Indol-3-yl)-2-[2-(4-phenyl...)
Show SMILES COC(=O)CC(=O)N(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(CC1)c1ccccc1)Cc1ccccc1OC
Show InChI InChI=1S/C35H41N5O5/c1-44-32-15-9-6-10-26(32)23-40(34(42)21-35(43)45-2)24-28(20-27-22-36-31-14-8-7-13-30(27)31)37-33(41)25-38-16-18-39(19-17-38)29-11-4-3-5-12-29/h3-15,22,28,36H,16-21,23-25H2,1-2H3,(H,37,41)
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n/an/a 1.28n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligand

J Med Chem 39: 736-48 (1996)


Article DOI: 10.1021/jm950616c
BindingDB Entry DOI: 10.7270/Q20864C7
More data for this
Ligand-Target Pair