BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50284882'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-P receptor (Rattus norvegicus (rat))	BDBM50284882 (2-[2-(2-Methoxy-phenyl)-2-methylsulfanyl-acetyl]-4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on rat brain membranes.				Bioorg Med Chem Lett 5: 1591-1594 (1995) Article DOI: 10.1016/0960-894X(95)00277-Z BindingDB Entry DOI: 10.7270/Q2X92B74
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50284882 (2-[2-(2-Methoxy-phenyl)-2-methylsulfanyl-acetyl]-4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on human IM9 lymphoblasts cultured cell line.				Bioorg Med Chem Lett 5: 1591-1594 (1995) Article DOI: 10.1016/0960-894X(95)00277-Z BindingDB Entry DOI: 10.7270/Q2X92B74
TBA Curated by ChEMBL					More data for this Ligand-Target Pair