Found 5 hits Enz. Inhib. hit(s) with Target = 'Sucrase-isomaltase, intestinal' and Ligand = 'BDBM50375510' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat)) | BDBM50375510
(CHEMBL405957)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of rat isomaltase |
Bioorg Med Chem 16: 2734-40 (2008)
Article DOI: 10.1016/j.bmc.2008.01.032 BindingDB Entry DOI: 10.7270/Q2FB53T0 |
More data for this Ligand-Target Pair | |
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat)) | BDBM50375510
(CHEMBL405957)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of rat sucrase |
Bioorg Med Chem 16: 2734-40 (2008)
Article DOI: 10.1016/j.bmc.2008.01.032 BindingDB Entry DOI: 10.7270/Q2FB53T0 |
More data for this Ligand-Target Pair | |
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat)) | BDBM50375510
(CHEMBL405957)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description Inhibition of rat intestinal sucrase using sucrose as substrate |
J Med Chem 55: 10347-62 (2012)
Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX |
More data for this Ligand-Target Pair | |
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat)) | BDBM50375510
(CHEMBL405957)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description Inhibition of rat intestinal isomaltase using isomoltose as substrate |
J Med Chem 55: 10347-62 (2012)
Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX |
More data for this Ligand-Target Pair | |
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat)) | BDBM50375510
(CHEMBL405957)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of rat intestinal maltase |
Bioorg Med Chem 16: 2734-40 (2008)
Article DOI: 10.1016/j.bmc.2008.01.032 BindingDB Entry DOI: 10.7270/Q2FB53T0 |
More data for this Ligand-Target Pair | |