Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Survival motor neuron protein' and Ligand = 'BDBM50242591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Survival motor neuron protein (Homo sapiens)	BDBM50242591 (CHEMBL4070751) Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C14H12ClFN2OS/c15-10-6-9(4-5-11(10)16)13(19)18-14-17-7-12(20-14)8-2-1-3-8/h4-8H,1-3H2,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
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