BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM50161097'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Synaptic vesicular amine transporter


(Rattus norvegicus (Rat))		BDBM50161097
PNG
(CHEMBL3793787)
Show SMILES Cl.OC[C@H](O)CN1[C@@H](CCc2ccc(O)cc2)CCC[C@H]1CCc1ccc(OCCF)cc1 |r|
Show InChI InChI=1S/C26H36FNO4.ClH/c27-16-17-32-26-14-8-21(9-15-26)5-11-23-3-1-2-22(28(23)18-25(31)19-29)10-4-20-6-12-24(30)13-7-20;/h6-9,12-15,22-23,25,29-31H,1-5,10-11,16-19H2;1H/t22-,23+,25-;/m1./s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 63n/an/an/an/an/an/an/an/a



University of Arkansas for Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ...

Bioorg Med Chem Lett 26: 2422-7 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.119
BindingDB Entry DOI: 10.7270/Q2BC41DT
More data for this
Ligand-Target Pair