Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM50534739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50534739 (CHEMBL4444122) Show SMILES Cl.Cl.Clc1ccccc1CCN1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C20H25ClN2/c21-20-9-5-4-8-19(20)11-13-23-16-14-22(15-17-23)12-10-18-6-2-1-3-7-18/h1-9H,10-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysis				Bioorg Med Chem Lett 26: 4441-4445 (2016) Article DOI: 10.1016/j.bmcl.2016.08.001 BindingDB Entry DOI: 10.7270/Q2Q81HK3
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50534739 (CHEMBL4444122) Show SMILES Cl.Cl.Clc1ccccc1CCN1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C20H25ClN2/c21-20-9-5-4-8-19(20)11-13-23-16-14-22(15-17-23)12-10-18-6-2-1-3-7-18/h1-9H,10-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...				Bioorg Med Chem Lett 26: 4441-4445 (2016) Article DOI: 10.1016/j.bmcl.2016.08.001 BindingDB Entry DOI: 10.7270/Q2Q81HK3
					More data for this Ligand-Target Pair