Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM125990'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM125990 (US8772297, Y284) Show SMILES CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)Nc2cccc(c2)-c2ccco2)CC1 Show InChI InChI=1S/C27H33N3O7S2/c1-27(2,3)37-26(31)30-14-12-20(13-15-30)19-28-38(32,33)23-9-5-10-24(18-23)39(34,35)29-22-8-4-7-21(17-22)25-11-6-16-36-25/h4-11,16-18,20,28-29H,12-15,19H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University US Patent					Assay Description The biological activity of a compound was determined by measuring the activation of Smad3/Smad4 complex which is a transcription factor showing activ...				US Patent US8772297 (2014) BindingDB Entry DOI: 10.7270/Q2XS5T2N
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