Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM282799'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM282799 (6-(1-(4,4-difluorocyclohexyl)-4-(4-fluorophenyl)-1...) Show SMILES Fc1ccc(cc1)-c1ncn(C2CCC(F)(F)CC2)c1-c1ccc2ncc(C#N)n2n1 Show InChI InChI=1S/C22H17F3N6/c23-15-3-1-14(2-4-15)20-21(18-5-6-19-27-12-17(11-26)31(19)29-18)30(13-28-20)16-7-9-22(24,25)10-8-16/h1-6,12-13,16H,7-10H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NP9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM282799 (6-(1-(4,4-difluorocyclohexyl)-4-(4-fluorophenyl)-1...) Show SMILES Fc1ccc(cc1)-c1ncn(C2CCC(F)(F)CC2)c1-c1ccc2ncc(C#N)n2n1 Show InChI InChI=1S/C22H17F3N6/c23-15-3-1-14(2-4-15)20-21(18-5-6-19-27-12-17(11-26)31(19)29-18)30(13-28-20)16-7-9-22(24,25)10-8-16/h1-6,12-13,16H,7-10H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.9	n/a	n/a	n/a	n/a	7.4	25
Rigel Pharmaceuticals, Inc.; Bristol-Myers Squibb Company US Patent					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				US Patent US9884868 (2018) BindingDB Entry DOI: 10.7270/Q20P122M
					More data for this Ligand-Target Pair