Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM283083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM283083 (6-(2-(4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2- ...) Show SMILES NC(=O)c1cnc2ccc(cn12)-c1c(nc2CCCn12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H16FN5O/c21-14-6-3-12(4-7-14)18-19(25-9-1-2-17(25)24-18)13-5-8-16-23-10-15(20(22)27)26(16)11-13/h3-8,10-11H,1-2,9H2,(H2,22,27)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NP9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM283083 (6-(2-(4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2- ...) Show SMILES NC(=O)c1cnc2ccc(cn12)-c1c(nc2CCCn12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H16FN5O/c21-14-6-3-12(4-7-14)18-19(25-9-1-2-17(25)24-18)13-5-8-16-23-10-15(20(22)27)26(16)11-13/h3-8,10-11H,1-2,9H2,(H2,22,27)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	25
Rigel Pharmaceuticals, Inc.; Bristol-Myers Squibb Company US Patent					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				US Patent US9884868 (2018) BindingDB Entry DOI: 10.7270/Q20P122M
					More data for this Ligand-Target Pair