Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM283089'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM283089 (4-(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H-...) Show SMILES FC(F)Cn1cnc(c1-c1ccc2ncc(N3CCOCC3)n2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H20F3N5O/c23-17-4-1-15(2-5-17)21-22(29(14-27-21)13-18(24)25)16-3-6-19-26-11-20(30(19)12-16)28-7-9-31-10-8-28/h1-6,11-12,14,18H,7-10,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	376	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NP9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM283089 (4-(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H-...) Show SMILES FC(F)Cn1cnc(c1-c1ccc2ncc(N3CCOCC3)n2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H20F3N5O/c23-17-4-1-15(2-5-17)21-22(29(14-27-21)13-18(24)25)16-3-6-19-26-11-20(30(19)12-16)28-7-9-31-10-8-28/h1-6,11-12,14,18H,7-10,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	376	n/a	n/a	n/a	n/a	7.4	25
Rigel Pharmaceuticals, Inc.; Bristol-Myers Squibb Company US Patent					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				US Patent US9884868 (2018) BindingDB Entry DOI: 10.7270/Q20P122M
					More data for this Ligand-Target Pair