Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM346294'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM346294 (US10202377, Compound 154) Show SMILES C(NCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccccn1)C1CCCC1 Show InChI InChI=1S/C30H28N8/c1-2-7-19(6-1)14-31-15-20-12-21(17-32-16-20)26-13-23-27(18-34-26)37-38-29(23)30-35-25-10-5-8-22(28(25)36-30)24-9-3-4-11-33-24/h3-5,8-13,16-19,31H,1-2,6-7,14-15H2,(H,35,36)(H,37,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
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