Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50015660'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50015660 (CHEMBL3260574 | USRE47141, Example 51) Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2OC(F)(F)F)nc1-c1ccc2ncnn2c1 Show InChI InChI=1S/C23H18F3N7O/c1-14-5-4-7-17(30-14)22-21(15-9-10-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-6-2-3-8-18(16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assay				J Med Chem 57: 4213-38 (2014) Article DOI: 10.1021/jm500115w BindingDB Entry DOI: 10.7270/Q2DV1MFM
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50015660 (CHEMBL3260574 | USRE47141, Example 51) Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2OC(F)(F)F)nc1-c1ccc2ncnn2c1 Show InChI InChI=1S/C23H18F3N7O/c1-14-5-4-7-17(30-14)22-21(15-9-10-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-6-2-3-8-18(16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION US Patent					Assay Description ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...				US Patent USRE47141 (2018) BindingDB Entry DOI: 10.7270/Q26W9D4M
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50015660 (CHEMBL3260574 | USRE47141, Example 51) Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2OC(F)(F)F)nc1-c1ccc2ncnn2c1 Show InChI InChI=1S/C23H18F3N7O/c1-14-5-4-7-17(30-14)22-21(15-9-10-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-6-2-3-8-18(16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radioisotopic assay				J Med Chem 57: 4213-38 (2014) Article DOI: 10.1021/jm500115w BindingDB Entry DOI: 10.7270/Q2DV1MFM
					More data for this Ligand-Target Pair