Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50151349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151349 (4-(5-Chloro-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...) Show SMILES Nc1nc(c(s1)-c1ccnc2ccccc12)-c1ccc(Cl)cn1 Show InChI InChI=1S/C17H11ClN4S/c18-10-5-6-14(21-9-10)15-16(23-17(19)22-15)12-7-8-20-13-4-2-1-3-11(12)13/h1-9H,(H2,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.864-3.661)				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151349 (4-(5-Chloro-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...) Show SMILES Nc1nc(c(s1)-c1ccnc2ccccc12)-c1ccc(Cl)cn1 Show InChI InChI=1S/C17H11ClN4S/c18-10-5-6-14(21-9-10)15-16(23-17(19)22-15)12-7-8-20-13-4-2-1-3-11(12)13/h1-9H,(H2,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair