Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50151355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151355 (5-[1,8]Naphthyridin-4-yl-4-pyridin-2-yl-thiazol-2-...) Show SMILES Nc1nc(c(s1)-c1ccnc2ncccc12)-c1ccccn1 Show InChI InChI=1S/C16H11N5S/c17-16-21-13(12-5-1-2-7-18-12)14(22-16)10-6-9-20-15-11(10)4-3-8-19-15/h1-9H,(H2,17,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (3.221-19.588)				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151355 (5-[1,8]Naphthyridin-4-yl-4-pyridin-2-yl-thiazol-2-...) Show SMILES Nc1nc(c(s1)-c1ccnc2ncccc12)-c1ccccn1 Show InChI InChI=1S/C16H11N5S/c17-16-21-13(12-5-1-2-7-18-12)14(22-16)10-6-9-20-15-11(10)4-3-8-19-15/h1-9H,(H2,17,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair