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Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50320960'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50320960
PNG
(3-((3-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2...)
Show SMILES Cc1cccc(n1)-c1nn(Cc2cccc(c2)C#N)cc1-c1ccc2ncccc2n1
Show InChI InChI=1S/C25H18N6/c1-17-5-2-8-24(28-17)25-20(21-10-11-22-23(29-21)9-4-12-27-22)16-31(30-25)15-19-7-3-6-18(13-19)14-26/h2-13,16H,15H2,1H3
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MMDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 318n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells

Bioorg Med Chem 18: 4459-67 (2010)


Article DOI: 10.1016/j.bmc.2010.04.071
BindingDB Entry DOI: 10.7270/Q2RV0NWK
More data for this
Ligand-Target Pair