Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University Curated by ChEMBL | Assay Description Inhibition of telomerase in human HepG2 cells after 24 hrs by TRAP-PCR-ELISA assay | Bioorg Med Chem 20: 6356-65 (2012) Article DOI: 10.1016/j.bmc.2012.08.059 BindingDB Entry DOI: 10.7270/Q2B85977 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University of Technology Curated by ChEMBL | Assay Description Inhibition of telomerase in human HepG2 cells after 48 hrs by TRAP-PCR-ELISA | Eur J Med Chem 60: 23-8 (2013) Article DOI: 10.1016/j.ejmech.2012.11.039 BindingDB Entry DOI: 10.7270/Q25M6710 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University Curated by ChEMBL | Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay | Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M | |||||||||||
More data for this Ligand-Target Pair |