Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50066357'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50066357 (3-(1-Methyl-piperidinium-1-yl)-N-{4-[3-(1-methyl-p...) Show SMILES C[N+]1(CCC(=O)Nc2ccc(NC(=O)CC[N+]3(C)CCCCC3)c3C(=O)c4ccccc4C(=O)c23)CCCCC1 Show InChI InChI=1S/C32H40N4O4/c1-35(17-7-3-8-18-35)21-15-27(37)33-25-13-14-26(34-28(38)16-22-36(2)19-9-4-10-20-36)30-29(25)31(39)23-11-5-6-12-24(23)32(30)40/h5-6,11-14H,3-4,7-10,15-22H2,1-2H3/p+2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of telomerase activity				J Med Chem 41: 3253-60 (1998) Article DOI: 10.1021/jm9801105 BindingDB Entry DOI: 10.7270/Q2TX3G1R
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50066357 (3-(1-Methyl-piperidinium-1-yl)-N-{4-[3-(1-methyl-p...) Show SMILES C[N+]1(CCC(=O)Nc2ccc(NC(=O)CC[N+]3(C)CCCCC3)c3C(=O)c4ccccc4C(=O)c23)CCCCC1 Show InChI InChI=1S/C32H40N4O4/c1-35(17-7-3-8-18-35)21-15-27(37)33-25-13-14-26(34-28(38)16-22-36(2)19-9-4-10-20-36)30-29(25)31(39)23-11-5-6-12-24(23)32(30)40/h5-6,11-14H,3-4,7-10,15-22H2,1-2H3/p+2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity of telomerase was measured using the TRAP assay.				J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD
					More data for this Ligand-Target Pair