Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50070942 ((-)-Epigallocatechin gallate | (-)-Epigallocatechi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of telomerase in human U937 cells | J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50070942 ((-)-Epigallocatechin gallate | (-)-Epigallocatechi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo... | J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50070942 ((-)-Epigallocatechin gallate | (-)-Epigallocatechi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te... | J Med Chem 55: 3678-86 (2012) Article DOI: 10.1021/jm201191d BindingDB Entry DOI: 10.7270/Q2DF6SB3 | |||||||||||
More data for this Ligand-Target Pair |