Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50253692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50253692 ((S)-2-Amino-N-(2-{6-[3-((S)-2-amino-3-methyl-butyr...) Show SMILES CC(C)[C@H](N)C(=O)NCCC(=O)Nc1ccc2C(=O)c3cc(NC(=O)CCNC(=O)[C@@H](N)C(C)C)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C30H38N6O6/c1-15(2)25(31)29(41)33-11-9-23(37)35-17-5-7-19-21(13-17)27(39)20-8-6-18(14-22(20)28(19)40)36-24(38)10-12-34-30(42)26(32)16(3)4/h5-8,13-16,25-26H,9-12,31-32H2,1-4H3,(H,33,41)(H,34,42)(H,35,37)(H,36,38)/t25-,26-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of telomerase in human JR8 cells by TRAP assay				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
					More data for this Ligand-Target Pair