Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50401016'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50401016 (CHEMBL2203643) Show SMILES CN(C)CCCNc1nc(nc2ccccc12)-c1ccc(Cl)cc1NC(=O)CCCN1CCN(C)CC1 Show InChI InChI=1S/C28H38ClN7O/c1-34(2)14-7-13-30-27-22-8-4-5-9-24(22)32-28(33-27)23-12-11-21(29)20-25(23)31-26(37)10-6-15-36-18-16-35(3)17-19-36/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3,(H,31,37)(H,30,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human telomerase in cell free system after 1 min by TRAP-LIG assay				Eur J Med Chem 47: 299-311 (2012) Article DOI: 10.1016/j.ejmech.2011.10.057 BindingDB Entry DOI: 10.7270/Q2V40WCF
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