Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50401018'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50401018 (CHEMBL2203649) Show SMILES CN(C)CCCNc1nc(nc2ccccc12)-c1ccc(Cl)cc1NC(=O)CN1CCN(C)CC1 Show InChI InChI=1S/C26H34ClN7O/c1-32(2)12-6-11-28-25-20-7-4-5-8-22(20)30-26(31-25)21-10-9-19(27)17-23(21)29-24(35)18-34-15-13-33(3)14-16-34/h4-5,7-10,17H,6,11-16,18H2,1-3H3,(H,29,35)(H,28,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human telomerase in cell free system after 1 min by TRAP-LIG assay				Eur J Med Chem 47: 299-311 (2012) Article DOI: 10.1016/j.ejmech.2011.10.057 BindingDB Entry DOI: 10.7270/Q2V40WCF
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