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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thioredoxin' and Ligand = 'BDBM50426062'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thioredoxin


(Homo sapiens (Human))		BDBM50426062
PNG
(CHEMBL2315288)
Show SMILES Nn1c(SSC2CCCCC2)nnc1-c1ccccc1
Show InChI InChI=1S/C14H18N4S2/c15-18-13(11-7-3-1-4-8-11)16-17-14(18)20-19-12-9-5-2-6-10-12/h1,3-4,7-8,12H,2,5-6,9-10,15H2
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MMDB

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...

J Med Chem 56: 1301-10 (2013)


Article DOI: 10.1021/jm301775s
BindingDB Entry DOI: 10.7270/Q2HQ4181
More data for this
Ligand-Target Pair