Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50105955'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105955 (3-Hydroxy-4-{N'-[3-methyl-1-(2-nitro-phenyl)-5-oxo...) Show SMILES Cc1[nH]n(-c2ccccc2[N+]([O-])=O)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:17.19| Show InChI InChI=1S/C20H15N5O7S/c1-11-18(20(27)24(23-11)14-8-4-5-9-15(14)25(28)29)21-22-19-13-7-3-2-6-12(13)17(10-16(19)26)33(30,31)32/h2-10,23,26H,1H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair