Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50105973'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105973 (4-{N'-[3-tert-Butyl-1-(3,4-dimethyl-phenyl)-5-oxo-...) Show SMILES Cc1ccc(cc1C)-n1[nH]c(c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O)C(C)(C)C |w:13.14| Show InChI InChI=1S/C25H26N4O5S/c1-14-10-11-16(12-15(14)2)29-24(31)22(23(28-29)25(3,4)5)27-26-21-18-9-7-6-8-17(18)20(13-19(21)30)35(32,33)34/h6-13,28,30H,1-5H3,(H,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair