Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50179469'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50179469 (5-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...) Show SMILES CC(C)(C)c1ccc(cc1)-c1cccc(n1)-c1nc2ccc(C=C3SC(S)=NC3=O)cc2[nH]1 |w:22.23,c:28| Show InChI InChI=1S/C26H22N4OS2/c1-26(2,3)17-10-8-16(9-11-17)18-5-4-6-20(27-18)23-28-19-12-7-15(13-21(19)29-23)14-22-24(31)30-25(32)33-22/h4-14H,1-3H3,(H,28,29)(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR				Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM
					More data for this Ligand-Target Pair