Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50179471'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50179471 (5-[1-[2-(4'-tert-Butyl-2-hydroxy-biphenyl-3-yl)-1H...) Show SMILES CC(C)(C)c1ccc(cc1)-c1cccc(-c2nc3ccc(C=C4SC(=S)NC4=O)cc3[nH]2)c1O |w:21.21| Show InChI InChI=1S/C27H23N3O2S2/c1-27(2,3)17-10-8-16(9-11-17)18-5-4-6-19(23(18)31)24-28-20-12-7-15(13-21(20)29-24)14-22-25(32)30-26(33)34-22/h4-14,31H,1-3H3,(H,28,29)(H,30,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR				Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM
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