Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50377380'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50377380 (CHEMBL260089) Show SMILES Fc1cccc2-c3nc(NC(=O)c4ccc(Nc5ccncn5)cc4)sc3COc12 Show InChI InChI=1S/C21H14FN5O2S/c22-15-3-1-2-14-18-16(10-29-19(14)15)30-21(26-18)27-20(28)12-4-6-13(7-5-12)25-17-8-9-23-11-24-17/h1-9,11H,10H2,(H,23,24,25)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TPO receptor				Bioorg Med Chem Lett 18: 3000-6 (2008) Article DOI: 10.1016/j.bmcl.2008.03.052 BindingDB Entry DOI: 10.7270/Q2474BRS
					More data for this Ligand-Target Pair