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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase' and Ligand = 'BDBM50378683'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thymidine phosphorylase


(Rattus norvegicus)		BDBM50378683
PNG
(CHEMBL599132)
Show SMILES Cc1cn(CC(OCP(O)(O)=O)Oc2ccccc2)c(=O)[nH]c1=O
Show InChI InChI=1S/C14H17N2O7P/c1-10-7-16(14(18)15-13(10)17)8-12(22-9-24(19,20)21)23-11-5-3-2-4-6-11/h2-7,12H,8-9H2,1H3,(H,15,17,18)(H2,19,20,21)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 750n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate

Bioorg Med Chem Lett 20: 862-5 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.081
BindingDB Entry DOI: 10.7270/Q2930V4K
More data for this
Ligand-Target Pair