Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase' and Ligand = 'BDBM50378684'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378684 (CHEMBL599543) Show SMILES Cc1cn([C@H]2C[C@H](CO)N(C2)C(=O)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H16N3O7P/c1-6-3-13(10(17)12-9(6)16)7-2-8(5-15)14(4-7)11(18)22(19,20)21/h3,7-8,15H,2,4-5H2,1H3,(H,12,16,17)(H2,19,20,21)/t7-,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
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