Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase' and Ligand = 'BDBM50378685'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378685 (CHEMBL599544) Show SMILES Cc1cn([C@H]2C[C@H](CO)N(CP(O)(O)=O)C2)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H18N3O6P/c1-7-3-14(11(17)12-10(7)16)8-2-9(5-15)13(4-8)6-21(18,19)20/h3,8-9,15H,2,4-6H2,1H3,(H,12,16,17)(H2,18,19,20)/t8-,9+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
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