Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase' and Ligand = 'BDBM50378689'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378689 (CHEMBL599563) Show SMILES Cc1cn([C@@H]2CN(CP(O)(O)=O)C[C@@H]2O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H16N3O6P/c1-6-2-13(10(16)11-9(6)15)7-3-12(4-8(7)14)5-20(17,18)19/h2,7-8,14H,3-5H2,1H3,(H,11,15,16)(H2,17,18,19)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
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