Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor alpha/beta' and Ligand = 'BDBM50163888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha/beta (Homo sapiens (Human))	BDBM50163888 (CHEMBL183176 | N-[4-(3-Isopropyl-1H-indol-5-yloxy)...) Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C23H20F6N2O4/c1-4-34-21(33)20(32)31-12-7-16(22(24,25)26)19(17(8-12)23(27,28)29)35-13-5-6-18-14(9-13)15(10-30-18)11(2)3/h5-11,30H,4H2,1-3H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells				Bioorg Med Chem Lett 15: 1835-40 (2005) Article DOI: 10.1016/j.bmcl.2005.02.028 BindingDB Entry DOI: 10.7270/Q290239F
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