Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Thyrotropin-releasing hormone receptor' and Ligand = 'BDBM50072395'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyrotropin-releasing hormone receptor (MOUSE)	BDBM50072395 (1-[3-cyclohexyl-2-(5-oxotetrahydro-1H-2-pyrrolylca...) Show SMILES [H][C@]1(CCC(=O)N1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C19H30N4O4/c20-17(25)15-7-4-10-23(15)19(27)14(11-12-5-2-1-3-6-12)22-18(26)13-8-9-16(24)21-13/h12-15H,1-11H2,(H2,20,25)(H,21,24)(H,22,26)/t13-,14-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Ability to bind thyroliberin endocrine receptor (TRH-R) using AtT-20 mouse pituitary tumor cells.				Bioorg Med Chem Lett 8: 3093-6 (1999) Article DOI: 10.1016/S0960-894X(98)00567-8 BindingDB Entry DOI: 10.7270/Q21R6PP1
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (MOUSE)	BDBM50072395 (1-[3-cyclohexyl-2-(5-oxotetrahydro-1H-2-pyrrolylca...) Show SMILES [H][C@]1(CCC(=O)N1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C19H30N4O4/c20-17(25)15-7-4-10-23(15)19(27)14(11-12-5-2-1-3-6-12)22-18(26)13-8-9-16(24)21-13/h12-15H,1-11H2,(H2,20,25)(H,21,24)(H,22,26)/t13-,14-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Ability to activate thyroliberin endocrine receptor (TRH-R) using AtT-20 mouse pituitary tumor cells prelabelled with myo-[3H] inositol				Bioorg Med Chem Lett 8: 3093-6 (1999) Article DOI: 10.1016/S0960-894X(98)00567-8 BindingDB Entry DOI: 10.7270/Q21R6PP1
					More data for this Ligand-Target Pair