Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM298055'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM298055 (3-[4-(2-fluorophenyl)-1,3-thiazol-2-yl]-7-(piperid...) Show SMILES Fc1ccccc1-c1csc(n1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1 Show InChI InChI=1S/C20H18FN5OS/c21-15-4-2-1-3-13(15)16-11-28-20(24-16)14-10-23-26-17(9-18(27)25-19(14)26)12-5-7-22-8-6-12/h1-4,9-12,22H,5-8H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10118930 (2018) BindingDB Entry DOI: 10.7270/Q2QC05J5
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