Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50088984'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50088984 (2-Benzenesulfonylamino-N-[1-(1-carbamimidoyl-2-hyd...) Show SMILES C[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)c1ccccc1)C(=O)N[C@H]1CCCN(C1O)C(N)=N Show InChI InChI=1S/C18H28N6O6S/c1-11(15(26)22-13-8-5-9-24(17(13)28)18(19)20)21-16(27)14(10-25)23-31(29,30)12-6-3-2-4-7-12/h2-4,6-7,11,13-14,17,23,25,28H,5,8-10H2,1H3,(H3,19,20)(H,21,27)(H,22,26)/t11-,13-,14+,17?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description The compound was tested in vitro for its inhibitory activity against human t-PA enzyme, activity expressed as IC50				Bioorg Med Chem Lett 10: 983-7 (2000) BindingDB Entry DOI: 10.7270/Q2765DKB
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