Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50115859'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50115859 (6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-2-ylmethoxy)-p...) Show SMILES NC(=N)c1cc2[nH]c(nc2cc1F)-c1cccc(OC[C@H]2CCCN2)c1O Show InChI InChI=1S/C19H20FN5O2/c20-13-8-15-14(7-12(13)18(21)22)24-19(25-15)11-4-1-5-16(17(11)26)27-9-10-3-2-6-23-10/h1,4-5,7-8,10,23,26H,2-3,6,9H2,(H3,21,22)(H,24,25)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of tissue-type plasminogen activator				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair