Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50147425'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50147425 (CHEMBL107872 | N-(7-Benzyloxy-isoquinolin-1-yl)-gu...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1nccc2ccc(-[#8]-[#6]-c3ccccc3)cc12 Show InChI InChI=1S/C17H16N4O/c18-17(19)21-16-15-10-14(7-6-13(15)8-9-20-16)22-11-12-4-2-1-3-5-12/h1-10H,11H2,(H4,18,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human tissue type plasminogen activator using S-2444				Bioorg Med Chem Lett 14: 3227-30 (2004) Article DOI: 10.1016/j.bmcl.2004.03.094 BindingDB Entry DOI: 10.7270/Q2125S3C
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