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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50194741'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tissue-type plasminogen activator


(Homo sapiens (Human))		BDBM50194741
PNG
(CHEMBL385158 | diphenyl 1-[(N-benzenesulfonyl-D-se...)
Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]S(=O)(=O)c1ccccc1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1
Show InChI InChI=1S/C33H37N6O8PS/c1-23(36-32(42)29(22-40)39-49(44,45)28-15-9-4-10-16-28)31(41)38-30(21-24-17-19-25(20-18-24)37-33(34)35)48(43,46-26-11-5-2-6-12-26)47-27-13-7-3-8-14-27/h2-20,23,29-30,39-40H,21-22H2,1H3,(H,36,42)(H,38,41)(H4,34,35,37)/t23-,29+,30?/m0/s1
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Similars
Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of recombinant tPA

J Med Chem 49: 5785-93 (2006)


Article DOI: 10.1021/jm060622g
BindingDB Entry DOI: 10.7270/Q2SF2VT3
More data for this
Ligand-Target Pair