Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 4 (Homo sapiens (Human)) | BDBM50011409 (CHEMBL3261261) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a |
Griffith University Curated by ChEMBL | Assay Description Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assay | J Med Chem 57: 1252-75 (2014) Article DOI: 10.1021/jm401321v BindingDB Entry DOI: 10.7270/Q2N01823 | |||||||||||
More data for this Ligand-Target Pair |