Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM419219'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM419219 (US10457681, Compound Ia-04 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC)cc5Sc4c3)c2n1 Show InChI InChI=1S/C25H29N7O2S/c1-4-5-10-34-24-29-22(26)21-23(30-24)32(25(33)28-21)14-16-7-9-18-20(12-16)35-19-11-15(13-27-2)6-8-17(19)31(18)3/h6-9,11-12,27H,4-5,10,13-14H2,1-3H3,(H,28,33)(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...				US Patent US10487084 (2019) BindingDB Entry DOI: 10.7270/Q2P55QX7
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM419219 (US10457681, Compound Ia-04 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC)cc5Sc4c3)c2n1 Show InChI InChI=1S/C25H29N7O2S/c1-4-5-10-34-24-29-22(26)21-23(30-24)32(25(33)28-21)14-16-7-9-18-20(12-16)35-19-11-15(13-27-2)6-8-17(19)31(18)3/h6-9,11-12,27H,4-5,10,13-14H2,1-3H3,(H,28,33)(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Companay US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...				US Patent US10981914 (2021) BindingDB Entry DOI: 10.7270/Q23X89RG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM419219 (US10457681, Compound Ia-04 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC)cc5Sc4c3)c2n1 Show InChI InChI=1S/C25H29N7O2S/c1-4-5-10-34-24-29-22(26)21-23(30-24)32(25(33)28-21)14-16-7-9-18-20(12-16)35-19-11-15(13-27-2)6-8-17(19)31(18)3/h6-9,11-12,27H,4-5,10,13-14H2,1-3H3,(H,28,33)(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Bristol_Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...				US Patent US10457681 (2019) BindingDB Entry DOI: 10.7270/Q2N87D54
					More data for this Ligand-Target Pair