Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50354945'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50354945 (CHEMBL1837067) Show SMILES CN1CCN(CC2CCCN2c2ncccc2Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)CC1 Show InChI InChI=1S/C23H29F3N8O/c1-31-8-10-32(11-9-31)14-16-5-3-7-33(16)21-15(4-2-6-28-21)13-34-17-12-18(23(24,25)26)29-20(27)19(17)30-22(34)35/h2,4,6,12,16H,3,5,7-11,13-14H2,1H3,(H2,27,29)(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TLR7 in human PBMC assessed as induction of type 1 interferon production				Bioorg Med Chem Lett 21: 5939-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.076 BindingDB Entry DOI: 10.7270/Q2PK0GJN
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