Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50380501'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50380501 (CHEMBL2018901) Show SMILES CCCCc1nc2c(N)nc3ccc(NC(=O)CCCCCCC(=O)Nc4ccc5nc(N)c6nc(CCCC)n(Cc7ccc(CN)cc7)c6c5c4)cc3c2n1Cc1ccc(CN)cc1 Show InChI InChI=1S/C52H62N12O2/c1-3-5-11-43-61-47-49(63(43)31-35-19-15-33(29-53)16-20-35)39-27-37(23-25-41(39)59-51(47)55)57-45(65)13-9-7-8-10-14-46(66)58-38-24-26-42-40(28-38)50-48(52(56)60-42)62-44(12-6-4-2)64(50)32-36-21-17-34(30-54)18-22-36/h15-28H,3-14,29-32,53-54H2,1-2H3,(H2,55,59)(H2,56,60)(H,57,65)(H,58,66)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assay				J Med Chem 55: 1106-16 (2012) Article DOI: 10.1021/jm2010207 BindingDB Entry DOI: 10.7270/Q2VH5PVX
					More data for this Ligand-Target Pair