Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM301880'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM301880 (2-Amino-N4-(cyclopropylmethyl)-N8-(5-ethoxy-3-pyri...) Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1 |t:11,20| Show InChI InChI=1S/C26H31N5O3/c1-3-9-31(16-17-5-6-17)26(33)20-10-18-7-8-19(11-23(18)30-24(27)12-20)25(32)29-21-13-22(34-4-2)15-28-14-21/h7-8,10-11,13-15,17H,3-6,9,12,16H2,1-2H3,(H2,27,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
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